Perfusion Clinical Resources


The following documents, created by AmSECT, are essential to differentiate, have specific backgrounds, and intentions of use. While the design of each one is to help standardize and improve the conduct of CPB, they differ by level of evidence and approval.

Clinical Practice Guidelines

There is a strict methodology for creating and approving the Clinical Practice Guidelines. An extensive research project determined which evidence-based, published literature documents would be used as references to develop these Clinical Practice Guidelines.

The Society of Thoracic Surgeons (STS) and The Society of Cardiovascular Anesthesiologists (SCA) are co-authors of these documents:

STS/SCA/AmSECT/SABM: Update to the Clinical Practice Guidelines on Patient Blood Management (2021)
STS/SCA/AmSECT: Clinical Practice Guidelines-- Anticoagulation During Cardiopulmonary Bypass (2018)
STS/SCA/AmSECT: Cardiopulmonary Bypass-- Temperature Managment during Cardiopulmonary Bypass (2015)
STS/SCA/AmSECT: Clinical Practice Guidelines-- Inflammatory Response to Adult Cardiopulmonary Bypass (2014)
STS/SCA/AmSECT: Blood Conservation (2011)

Clinical Protocols

The Clinical Protocols generate from various institutional protocols, published literature, and committee consensus. While these documents have less rigorous requirements, they are still evidence-based and help serve as a template to compliment or initiate your institutional protocols.

The first ten releases focus on Special Patient Populations. These serve as a basic introduction to the disease and/or pathology and any specific perfusion-related procedures or knowledge necessary to provide adequate care for Special Patient populations receiving cardiopulmonary bypass.

Acute Normovolemic Hemodilution
AngioVac Aspiration System
Antiphospholipid Syndrome
Bleomycin Toxicity
Cold Agglutinins
Deep Hypothermic Circulatory Arrest
Heparin Induced Thrombocytopenia
Hyperthermic Intraperitoneal Chemotherapy
Intraoperative Therapeutic Plasma Exchange
Jehovah’s Witness
Left Heart Bypass
Malignant Hyperthermia
Massive Air Embolism
Pregnant Patient
Pulmonary Artery Flow Study
Retrograde Cerebral Perfusion
Sickle Cell Disease
Vacuum-Assisted Venous Drainage

Pediatric Clinical Protocols

Pulmonary Artery Flow Study for Unifocalizations 
Therapeutic Plasma Exchange (TPE) During Cardiopulmonary Bypass (CPB)

Standards and Guidelines

AmSECT’s Standards and Guidelines for Perfusion Practice were created as a checklist or template to ensure your department is following what is expected of a perfusion team by its national society. The items listed are what AmSECT has determined are the minimum requirements for safe cardiopulmonary bypass.

View the Standards and Guidelines here.


Standards and Guidelines Implementation Toolkit

DO2 Chart
Patient Care Plan
Supply Chain Management
Orientation and Onboarding Template