Basic Pharmacological Concepts For Perfusionists
Part I

by

James E. Berger, PhD


NUMBER OF PAGES: 69 pages
COST: $8.00

Upon completion of the activities, the perfusionist should have mastered the below stated objectives with 100 percent accuracy:

  1. To define basic pharmacological terminologies

  2. To state basic pharmacodynamic concepts that apply to drug actions

  3. To relate the concept of dose response curves to a drug's pharmacological activity on a biological system

  4. To discuss the concept of a drug's margin of safety

  5. To explain the concept of drug-receptor interactions in the production of various pharmacological effects

  6. To identify pharmacokinetic principles that affect drug activity in the body based upon the drug's various chemical and physical properties, and relate how changes in these properties modify a drug's absorption, distribution, metabolism and excretion (ADME)

  7. To describe the meaning of bioavailability of a drug, its biotransfusion (metabolism) by various body tissues into active and inactive metabolites, and to give examples of physiological factors that affect drug dosages

  8. To define the concept of clinical pharmacology, explain the role of placebo in drug investigation and therapeutic practice, describe the development of a drug clinically for safety and efficacy and the steps involved in experimental drug testing until a drug reaches the market place

  9. To list the sources of drug information and describe basic pharmacology and therapeutic literature sources for future reference