Basic Pharmacological Concepts For Perfusionists Part I
by James E. Berger, PhD
NUMBER OF PAGES: 69 pages
COST: $8.00
Upon completion of the activities, the perfusionist should have mastered the
below stated objectives with 100 percent accuracy:
- To define basic pharmacological terminologies
- To state basic pharmacodynamic concepts that apply to drug actions
- To relate the concept of dose response curves to a drug's pharmacological activity on a biological system
- To discuss the concept of a drug's margin of safety
- To explain the concept of drug-receptor interactions in the production of various pharmacological effects
- To identify pharmacokinetic principles that affect drug activity in the body based upon the drug's various chemical and physical properties, and relate how changes in these properties modify a drug's absorption, distribution, metabolism and excretion (ADME)
- To describe the meaning of bioavailability of a drug, its biotransfusion (metabolism) by various body tissues into active and inactive metabolites, and to give examples of physiological factors that affect drug dosages
- To define the concept of clinical pharmacology, explain the role of placebo in drug investigation and therapeutic practice, describe the development of a drug clinically for safety and efficacy and the steps involved in experimental drug testing until a drug reaches the market place
- To list the sources of drug information and describe basic pharmacology and therapeutic literature sources for future reference
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