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"Despite the recent introduction of a number of technical and pharmacologic blood conservation measures, bleeding and allogeneic transfusion remain persistent problems in open-heart surgical procedures. Efforts should be made to decrease or completely avoid transfusions to avoid these negative reactions."1
1. A Cardiopulmonary Bypass Based Blood Management Strategy in Adult Cardiac Surgery.
Budak AB, McCusker K, Gunaydin S.
Heart Surg Forum. 2017 Oct 24;20(5):E195-E198 FREE